LNP Characterization
Helix's cryo-EM team brings specialized expertise in the structural characterization of liposomes and lipid nanoparticles.
Comprehensive Services
We provide customers with an end-to-end service that is customized to bring the project to success and typically includes LNP sample preparation, data collection, and data analysis.
Cutting-Edge Techniques
We provide services for three of the most effective characterization techniques for LNPs: Cryo-EM, SAXS, and DLS.
Rapid Turnaround Times
Our well-optimized workflows enable you to get the information
you require at the right time, thereby accelerating your research.
Your Partner in Discovery
Please do not hesitate to contact us and find out how our Cryo-EM, SAXS and DLS services can support your innovative LNP-based therapeutics. Helix BioStructures is happy to be your partner in the development of novel drug delivery systems.
Technique-based LNP Services
Cryo-EM: Visualizing LNPs with Unparalleled Detail
Cryo-Electron Microscopy offers high-resolution structural insights, providing critical information about LNP morphology and particle integrity.- Data Collection: 1 week- Outcome: Detailed structural snapshots that guide formulation optimization and stability assessment.
SAXS: Gaining Insights into Size and Shape
Small Angle X-ray Scattering excels at elucidating the overall size, shape, and assembly properties of your LNPs in solution.- Data Collection: 1 week- Analysis: 1–2 weeks- Outcome: Quantitative profiles that enable you to fine-tune particle dimensions and enhance therapeutic performance.
DLS: Rapid Quality Control for Particle Size
Dynamic Light Scattering provides a fast and reliable measure of particle size distribution and polydispersity.- Data Collection & Analysis: < 1 week- Outcome: Timely verification of homogeneity and stability—essential for robust LNP formulations.
Never feel lost in the process again
LNPs have become an essential delivery mechanism for RNA and other molecules in the pharmaceutical and agricultural industries. Characterizing LNPsallows researchers to develop and produce the most effective platform for delivering their next-generation molecules in an industrially efficient manner. AtHelix, we offer in-depth knowledge and a multi-technique characterization approach for your LNP formulations.